Overview

Our research focuses on exploiting the multiple non-covalent substrate-catalyst interactions (electrostatic interactions, Van der Waals forces, π-effects, hydrophobic effect ) for the design of synergetic asymmetric catalysis, to address selectivity challenges in synthetic chemistry, to make conceptual advances, to shed light on mechanistic understanding. The objective is to create new structural entities for catalysis, integrating rational design, organic synthesis, performance evaluation, mechanistic investigation and so on. Continuous efforts will be made to construct bioactive molecules including chiral compounds and natural product analogues and to study their corresponding bioactivities and interesting biofunctions as well.


Funding

Facilities and Equipment

Lab
Analytical HPLC with Autosampler (Shimadzu LC-20A)

School of Pharmaceutical Sciences

ZLL Lab in Xiamen University

Contact: Lili ZONG ( Lili.Zong@xmu.edu.cn)

Location: Zhuangjin Building, Room 316


NMR (Bruker Avance III, 600 MHz)

Contact: Cuiling SUN (0592-2881220, cuiling@xmu.edu.cn)

Location: Zhuangjin Building, Room102


LC-LRMS (Shimadzu LCMS-2020)

Contact: Yihong WU (0592-2189597, wuyihong@xmu.edu.cn)

Location: Zhuangjin Building, Room 101


LC-HRMS (Thermo Fisher Q Exactive)

Contact: Rong DING (0592-2881220, dingrong@xmu.edu.cn)

Location: Zhuangjin Building, Room 101


Preparative HPLC (Shimadzu LC-20AP)

Contact: Rong DING (0592-2881220, dingrong@xmu.edu.cn)

Location: Zhuangjin Building, Room 311


Flash Purification System (Biotage Isolera Prime))

Contact: Prof. Quancheng CHEN Group (0592-2881189, chenqc@xmu.edu.cn)

Location: Zhuangjin Building, Room 216


Polarimeter (Rudolph Autopol IV)

Contact: Lijuan WANG (0592-2189597, lijuan@xmu.edu.cn)

Location: Zhuangjin Building, Room 103


Fluorescence Spectrophotometer (Agilent Cary Eclipse)

Contact: Prof. Hu ZHOU Group

Location: Zhuangjin Building


Freeze-Dryer (Christ Alpha 2-4 LSC)

Contact: Prof. Haifeng CHEN Group

Location: Zhuangjin Building, Room 308


Confocal Microscope LSM 5 Exciter (Zeiss)

Contact: Ye YUN (0592-2187204, yunye@xmu.edu.cn)

Location: Zhuangjin Building, Room 427


Flow Cytometry (Beckman Coulter Epics Altra)

Contact: Yingpu TIAN (0592- 2187203, typ@xmu.edu.cn)

Location: Zhuangjin Building, Room 339


FTIR Spectrometer (Thermo Fisher Scientific Nicolet-380)

Contact: Lijuan WANG (0592-2189597, lijuan@xmu.edu.cn)

Location: Zhuangjin Building, Room 103


UV-Vis Spectrometer (Thermo Fisher Scientific Helios Alpha)

Contact: Junjie CHEN (0592- 2186260, chenjunjie@xmu.edu.cn)

Location: Zhuangjin Building, Room 330


Water Purification Systems (MilliporeSigma Elix 100) and Ice

Contact: Ye YUN (0592-2187204, yunye@xmu.edu.cn)

Location: Zhuangjin Building, Room 434